The prolific Norwegian striker had another chance later but defender Nico Elvedi blocked his effort.
The withdrawal of Osaka meant that two of the current world's top three women's players would not play at Roland Garros this year, as reigning champion and world No. 1 Ashleigh Barty already announced earlier this month that she would not be able to participate the clay major due to the COVID-19 pandemic.
Lewandowski also expects to see Bayern's new arrival Leroy Sane moving up a gear after joining in from Manchester City.
Garbine Muguruza, seeded ninth, eased into the final eight. The Spaniard beat Johanna Konta of Great Britain 6-4, 6-1. Enditem
The Arsenal captain scored a brace in last season's FA Cup final as Arsenal came from behind to beat Chelsea 2-1. He also netted in Arsenal's 3-0 victory over Fulham last Saturday in their first game of the new Premier League season.
The Royal Blues striker welcomed Germany's federal states' joint decision to allow the return of 20 percent of the fans in a test-phase until the end of October.
Celta received good news on Wednesday when they completed a move to bring Jeison Murillo back to the club for another season. Murillo was vital as Oscar Garcia's side escaped relegation last season and although the central defender won't play against Valencia on Saturday, his arrival is a major boost for the club.
"It's completely normal that we have to make another step because other teams will make other steps as well," said Klopp in an interview with Sky Sports News.
"The situation was complicated so it was important to win tonight. It's hard, we created some chances, but we're not 100%."
The victory for Pogacar was incredible, as he overcame long-term race leader Primoz Roglic, a fellow Slovenian cyclist, in a stunning time trial win in the penultimate stage on Saturday when he erased a 57-second deficit and even established an unshakable 59-second lead entering into Sunday's ceremonial route from Mantes-la-Jolie to Champs-Elysees.
His podium finish caught the eye of the officials of the International Association of Athletics Federations (IAAF), now renamed World Athletics, and he was selected to join their High Performance Training Centre in Dakar, Senegal.